DIAL - De novo Identification of Alleles Tool name | DIAL - De novo Identification of Alleles |
---|
URL |
http://www.bx.psu.edu/miller_lab/ |
---|
Important features | 1. DIAL (De novo Identification of Alleles), for identifying single-base substitutions between two closely related genomes without the help of a reference genome.
2. The method works even when the depth of coverage is insufficient for de novo assembly, and it can be extended to determine small insertions/deletions.
3. The use of DIAL to identify nucleotide differences among transcriptome sequences. |
---|
Citations | Ratan A, Zhang Y, Hayes VM, Schuster SC, Miller W.
Calling SNPs without a reference sequence.
BMC Bioinformatics. 2010 Mar 15;11:130.
PMID: 20230626 |
---|
Year of publication | 2010 |
---|
Rank by usage frequency | 100 |
---|
Comments | Requires installation of LASTZ in the path. |
---|
Function | SNP discovery |
---|
Category | Free, Downloadable |
---|
License | MIT |
---|
Status | |
---|
Input file format | SFF files for Roche 454, FASTQ for Illumina/Solexa |
---|
Output file format | |
---|
Operating system | Linux 64 bit |
---|
Operating language | C, Python |
---|
Platform | Illumina/Solexa, Roche 454 |
---|
Maintained by | Heracle BioSoft |
---|
Downloadable file format | |
---|
Submission file format | |
---|
| |